Clinical Guidelines

Clinical Guideline Development and Assessment

As an objective, independent resource, Spectrum Research can assist clinical groups and organizations to enhance the quality and usability of their guidelines.

The need for high-quality, evidence-based clinical practice guidelines (CPG) that have been developed with rigor and transparency has never been greater. The primary goal of clinical practice guidelines (CPG) is to promote the best possible patient outcomes based on diagnostic methods and treatments that work. Payers, policy makers, health-care systems, clinicians and patients all benefit from sound, updated guidelines.

The credibility of clinical guidelines largely rests on the rigor and transparency of their development.

Spectrum has experience in leading and managing multidisciplinary groups of clinicians to assist them with establishing evidence-based clinical recommendations for guidelines, position statements, and manuscripts.

Spectrum performs methodologically-sound systematic reviews and comparative effectiveness reviews and works interactively with such groups at all stages from the beginning of defining key questions and objectives through the creation of evidence-based clinical recommendations to help ensure that rigor is maintained together with important clinical perspectives.

Spectrum’s Process

Key elements and processes described by the Institute of Medicine (IOM), the National Guideline Clearinghouse (NGC) and Appraisal of Guidelines Research and Evaluation (AGREE) are used by Spectrum Research to assist professional groups and organizations to appraise, update and develop guidelines.

The process is tailored to individual client needs and includes:

  • Appraisal of existing guideline relative to development process and evidence base and linking of evidence and recommendations
  • Interactive development of appropriate objectives, topic focus and key questions with clinical experts and appropriate stakeholders
  • Perform and document systematic literature-review based on accepted methods for search, selection of relevant clinical research, critical appraisal of studies and determination of overall strength of evidence (See here)
  • Facilitate interactive discussion of evidence and its use to formulate appropriate clinical recommendations using processes such as a modified Delphi process
  • Assistance with ensuring clarity of recommendations and appropriate linking of relevant evidence